119280-58-9Relevant academic research and scientific papers
Biomimetic syntheses of neurotrophic americanola and isoamericanola by horseradish peroxidase (HRP) catalyzed oxidative coupling
Takahashi, Hironobu,Matsumoto, Keiji,Ueda, Masumi,Miyake, Youko,Fukuyama, Yoshiyasu
, p. 245 - 256 (2007/10/03)
Horseradish peroxidase (HRP) catalyzed oxidative coupling of caffeic acid has yielded novel dimeric compounds (8) and (9) having a 1,4-benzodioxane ring, which have been in turn converted to americanol A (1) and isoamericanol A (2) in a few steps respecti
Structures of americanol A and isoamericanol A having a neurotrophic property from the seeds of Phytolacca americana
Fukuyama,Hasegawa,Toda,Kodama,Okazaki
, p. 252 - 254 (2007/10/02)
The structures of new neo-lignans, isoamericanol A (1) and americanol A (2) isolated from the seeds of Phytolacca americana have been elucidated on the basis of spectroscopic data and then confirmed by chemical correlation with the previouslty known isoamericanin A (3) and americanin A (4). Isoamericanol A, americanol A, and americanin A have been found to enhance choline acetyltransferase activity at 10-5 M in a cultured neuronal cell system derived from fetal rat hemisphere.
