1192813-64-1

Basic information

• Product Name: 2-Chloro-5-(difluoromethoxy)pyrimidine
• Synonyms: 2-Chloro-5-(difluoromethoxy)pyrimidine;Pyrimidine, 2-chloro-5-(difluoromethoxy)-
• CAS NO: 1192813-64-1
• Molecular Formula: C₅H₃ClF₂N₂O
• Molecular Weight: 180.54
• EINECS: -0
• Mol File: 1192813-64-1.mol
• Article Data: 8

Chemical Properties

• Boiling Point: 260.1±30.0 °C(Predicted)
• Appearance: /
• Density: 1.466±0.06 g/cm3(Predicted)
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• PKA: -2.63±0.22(Predicted)
• CAS DataBase Reference: 2-Chloro-5-(difluoromethoxy)pyrimidine(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Chloro-5-(difluoromethoxy)pyrimidine(1192813-64-1)
• EPA Substance Registry System: 2-Chloro-5-(difluoromethoxy)pyrimidine(1192813-64-1)

Safety Data

• Hazardous Substances Data: 1192813-64-1(Hazardous Substances Data)

Upstream product

• 1514-87-0 metyhyl chlorodifluoroacetate 
• 4983-28-2 2-chloropyrimidine-5-ol 
• 667-27-6 Ethyl bromodifluoroacetate 
• 1895-39-2 sodium chlorodifluoroacetate 

Downstream Products

• 1544495-69-3 (1S,2S,3S)-2-(4-(5-(difluoromethoxy)pyrimidin-2-yl)phenyl)-1-fluoro-N-hydroxy-3-phenylcyclopropanecarboxamide 

Relevant articles and documents

PCSK9 INHIBITORS AND METHODS OF USE THEREOF

The invention relates to a novel inhibitor pharmacophore of PCSK9 and heteroaryl compounds that bind the PCSK9 protein.

PESTICIDALLY ACTIVE DIAZINE-AMIDE COMPOUNDS

Compounds of formula (I) wherein the substituents are as defined in claim 1, and the agrochemically acceptable salts, stereoisomers, enantiomers, tautomers and N-oxides of those compounds, can be used as insecticides.

Substituted Pyridine Compound

The present invention provides a substituted pyridine compound or a pharmacologically acceptable salt thereof which has excellent CETP inhibition activity and is useful as a medicament. The present invention provides a compound represented by a general formula (I), wherein R1 is H, optionally substituted alkyl, OH, optionally substituted alkoxy, alkylsulfonyl, optionally substituted amino, carboxy, optionally substituted carbonyl, CN, halogeno, optionally substituted phenyl, optionally substituted aromatic heterocyclyl, optionally substituted saturated heterocyclyl, optionally substituted saturated heterocyclyloxy or optionally substituted saturated heterocyclylcarbonyl, etc., and the like.