1192829-79-0

Upstream product

• 1192829-78-9 methyl 3-cyano-4-(cyclopropylmethoxy)benzoate 
• 156001-68-2 methyl 3-cyano-4-hydroxybenzoate 
• 29415-97-2 methyl 3-bromo-4-hydroxybenzoate 

Downstream Products

• 1192829-80-3 3-cyano-4-[(cyclopropylmethyl)oxy]benzoyl chloride 
• 1192829-98-3 1,1-dimethylethyl 3-[5-(5-{3-cyano-4-[(cyclopropylmethyl)oxy]phenyl}-1,2,4-oxadiazol-3-yl)-1-isoquinolinyl]propanoate 
• 1192829-54-1 3-[5-(5-{3-cyano-4-[(cyclopropylmethyl)oxy]phenyl}-1,2,4-oxadiazol-3-yl)-1-isoquinolinyl]propanoic acid 

Relevant academic research and scientific papers

SELECTIVE SPHINGOSINE 1 PHOSPHATE RECEPTOR MODULATORS AND COMBINATION THERAPY THEREWITH

Compounds that selectively modulate the sphingosine 1 phosphate receptor are provided, including compounds which modulate subtype 1 of the S1P receptor, and methods of their therapeutic and/or prophylactic use in combination with at least one other medicament adapted for treatement of a malcondition for which activation of S1P1 is medically indicated, such as multiple sclerosis.