119292-80-7

Basic information

• Product Name: 2-(3-chloropropyl ureido)benzamide
• CAS NO: 119292-80-7
• Molecular Weight: 255.704
• Mol File: 119292-80-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-(3-chloropropyl ureido)benzamide(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(3-chloropropyl ureido)benzamide(119292-80-7)
• EPA Substance Registry System: 2-(3-chloropropyl ureido)benzamide(119292-80-7)

Safety Data

• Hazardous Substances Data: 119292-80-7(Hazardous Substances Data)

Upstream product

• 13010-19-0 3-Chloropropyl isocyanate 
• 28144-70-9 anthranilic acid amide 

Downstream Products

• 94507-28-5 3,4-Dihydro-2H,6H-<1,3>oxazino<2,3-b>quinazolin-6-one 

Relevant articles and documents

Reactions of Anthranilamide with Isocyanates: A New Facile Synthesis of 2,3-Dihydro-5H-oxazoloquinazolin-5-one and 3,4-dihydro-2H,6H-oxazinoquinazolin-6-one

2,3-Dihydro-5H-oxazoloquinazolin-5-one 5a was synthesized from anthranilamide 1 and 2-chloroethyl isocyanate either by a direct reflux in methanol, or by stirring at room temperature in acetonitrile leading to the intermediate, 2-(2-chloroethyl ureido)benzamide 6a which was subsequently cyclized on heating with an organic base.However, when compound 6a was refluxed with concentrated hydrochloric acid, it furnished 3-(2-chloroethyl)-2,4-dioxo-1H,3H-quinazoline 2a in a good yields. 3,4-Dihydro-2H,6H-oxazinoquinazolin-6-one 5b, 3-(3-chloropropyl)-2,4-dioxo-1H,3H-quinazoline 2b and 2-(3-chloropropyl ureido)benzamide 6b were obtained similarly from 1 and 3-chloropropyl isocyanate.