119308-94-0Relevant articles and documents
Two new pyridine monoterpene alkaloids by chemical conversion of a commercial extract of Harpagophytum procumbens
Baghdikian,Ollivier,Faure,Debrauwer,Rathelot,Balansard
, p. 211 - 213 (2007/10/03)
The treatment of harpagide (1), harpagoside (2), or 8-O-p- coumaroylharpagide (3), the main iridoids of Harpagophytum procumbens and Harpagophytum zeyheri, with NH3 and HCl led to aucubinine B(4), a pyridine monoterpene alkaloid (PMTA). A similar procedure applied to a commercial extract of H. procumbens yielded 4 and two new PMTAs named beatrine A (5) and beatrine B (6). The structures of these new PMTAs were established using ESIMS and 2D NMR. Their semisynthesis was analyzed in terms of reaction mechanisms.