1193090-84-4

Basic information

• Product Name: (7-benzyl-7-azabicyclo[2.2.1]hept-1-ylmethyl)-pyridin-2-yl-amine
• Synonyms: (7-benzyl-7-azabicyclo[2.2.1]hept-1-ylmethyl)-pyridin-2-yl-amine
• CAS NO: 1193090-84-4
• Molecular Weight: 293.412
• Mol File: 1193090-84-4.mol

Chemical Properties

• CAS DataBase Reference: (7-benzyl-7-azabicyclo[2.2.1]hept-1-ylmethyl)-pyridin-2-yl-amine(CAS DataBase Reference)
• NIST Chemistry Reference: (7-benzyl-7-azabicyclo[2.2.1]hept-1-ylmethyl)-pyridin-2-yl-amine(1193090-84-4)
• EPA Substance Registry System: (7-benzyl-7-azabicyclo[2.2.1]hept-1-ylmethyl)-pyridin-2-yl-amine(1193090-84-4)

Safety Data

• Hazardous Substances Data: 1193090-84-4(Hazardous Substances Data)

Upstream product

• 109-04-6 2-bromo-pyridine 
• 1193090-83-3 C-(7-benzyl-7-azabicyclo[2.2.1]hept-1-yl)-methylamine 

Relevant articles and documents

A straightforward entry to 7-azabicyclo[2.2.1]heptane-l-carbonitriles in the synthesis of novel epibatidine analogues

This paper presents the synthesis of epibatidine analogues by a straightforward one-pot method for the synthesis of 7azabicyclo[2.2.1]heptane-1- carbonitriles, starting from cyclohexanones bearing a leaving group at the 4-position. In situ imine formation

STRAIGHTFORWARD ENTRY TO 7-AZABICYCLO[2.2.1]HEPTANE-1-CARBONITRILES AND SUBSEQUENT SYNTHESIS OF EPIBATIDINE ANALOGUES

The present invention relates to a group of substituted-7-azabicyclo-[2.2.1]heptyl derivatives with biological activity. The present invention also relates to synthetic methods for producing said substituted-7-azabicyclo-[2.2.1]heptyl derivatives. The present invention also relates to certain intermediates for producing such substituted-7-azabicyclo-[2.2.1]heptyl derivatives, as well as a synthetic method for producing such intermediates. The present invention also relates to pharmaceutical compositions comprising such substituted-7-azabicyclo-[2.2.1]heptyl derivatives, as well as their use as medicaments for the treatment of diseases mediated by a Nicotinic Acetylcholine Receptor or a receptor being a member of the Neurotransmitter-gated Ion Channel Superfamily, such as pain, Alzheimer's disease, Parkinson's disease, schizophrenia, epilepsy and nicotine addiction.