1193091-98-3Relevant academic research and scientific papers
Synthesis of 7-aza- and 7-thiasphingosines, and evaluation of their interaction with sphingosine kinases and with T-cells
Mathew, Thresen,Billaud, Celia,Billich, Andreas,Cavallari, Marco,Nussbaumer, Peter,De Libero, Gennaro,Vasella, Andrea
experimental part, p. 725 - 738 (2010/04/23)
The synthesis of 7-oxasphingosine (3) and 7-oxaceramide (4) was improved by starting from the 4-methoxybenzyl-protected d-galactal 9. The sphingosine analogues 5-7 and 24 were synthesized via the azido alcohol 13. The 7-thiasphingosine 5 is a poorer subst
