1193104-11-8

Basic information

• Product Name: 4-Chloro-2-(difluoromethyl)pyridine hydrochloride
• Synonyms: 4-Chloro-2-(difluoromethyl)pyridine hydrochloride;4-Chloro-2-(difluoromethyl)pyridine;EOS-61831
• CAS NO: 1193104-11-8
• Molecular Formula: C6H5Cl2F2N
• Molecular Weight: 200.0134064
• EINECS: 940-241-7
• Mol File: 1193104-11-8.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 163.8±35.0 °C(Predicted)
• Appearance: /
• Density: 1.334±0.06 g/cm3(Predicted)
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• PKA: 0.19±0.10(Predicted)
• CAS DataBase Reference: 4-Chloro-2-(difluoromethyl)pyridine hydrochloride(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Chloro-2-(difluoromethyl)pyridine hydrochloride(1193104-11-8)
• EPA Substance Registry System: 4-Chloro-2-(difluoromethyl)pyridine hydrochloride(1193104-11-8)

Safety Data

• Hazardous Substances Data: 1193104-11-8(Hazardous Substances Data)

Upstream product

• 1121-76-2 4-chloropyridine N-oxide 
• 63071-13-6 4-chloro-2-pyridinecarbaldehyde 
• 626-61-9 4-Chloropyridine 
• 7379-35-3 4-chlorpyridine hydrochloride 

Relevant articles and documents

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A diversity-oriented and C2-selective synthesis of difluoroalkyl-substituted heteroarenes from three fragments, N-methoxyazinium salts, difluorocarbene, and electrophilic or radical reagents, is described. The reaction proceeds via the addition of difluorinated phosphorus ylide to in situ methylated heteroarene N-oxides, leading to phosphonium salts, which can undergo further transformations under basic or photoinduced conditions.

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