119321-44-7Relevant academic research and scientific papers
S-ALKYLTHIOSEMICARBAZONIUM SALTS IN THE SYNTHESIS OF 1,2,4-TRIAZOLINES. MOLECULAR STRUCTURE OF 1,4-DIACETYL-3-(5-NITROFURFURYLTHIO)-5-(2-FURYL)-Δ2-1,2,4-TRIAZOLINE
Usova, E. B.,Krapivin, G. D.,Zavodnik, V. E.,Kul'nevich, V. G.
, p. 776 - 781 (2007/10/02)
Acylation of S-alkylthiosemicarbazonium salts with acetic anhydride leads to the formation of 1,4-diacetyl-Δ2-1,2,4-triazolines.It was also demonstrated, based on x-ray structural analysis, that the triazoline ring in the molecular structure of
4-Acetyl-1-(R-benzylidene)-3-(5-nitro-2-furfuryl)thiosemicarbazides - Carriers of Synthones for Obtaining Thiazole and Triazole Rings
Krapivin, G. D.,Usova, E. B.,Kul'nevich, V. G.
, p. 573 - 578 (2007/10/02)
The corresponding thiosemicarbazonium salts, which form 4-acetyl- and 2,4-diacetyl-1-benzylidene-3-(5-nitro-2-furfuryl)thiosemicarbazides with acetic anhydride, were obtained by the reaction of 5-nitrofurfuryl bromide with 1-benzylidenethiosemicarbazides.Under the influence of bases the monoacetylated derivatives undergo cyclization to the corresponding 2-benzylidenehydrazino-5-(5-nitro-2-furyl)thiazoles.Intramolecular cyclization of the monoacetylated products to 3-methyl-5--1,2,4-triazole, which is accompanied by the elimination of the corresponding benzaldehyde, occurs in the presence of hydrochloric acid.
