1193375-04-0

Basic information

• Product Name: spiro[(3-(3-methoxyphenyl)-6,6-dimethyl-4-oxo-2,3,4,5,6,7-hexahydrobenzofuran)-2,2'-(5,5-dimethylcyclohexane-1,3-dione)]
• Synonyms: spiro[(3-(3-methoxyphenyl)-6,6-dimethyl-4-oxo-2,3,4,5,6,7-hexahydrobenzofuran)-2,2'-(5,5-dimethylcyclohexane-1,3-dione)]
• CAS NO: 1193375-04-0
• Molecular Weight: 396.483
• Mol File: 1193375-04-0.mol

Chemical Properties

• CAS DataBase Reference: spiro[(3-(3-methoxyphenyl)-6,6-dimethyl-4-oxo-2,3,4,5,6,7-hexahydrobenzofuran)-2,2'-(5,5-dimethylcyclohexane-1,3-dione)](CAS DataBase Reference)
• NIST Chemistry Reference: spiro[(3-(3-methoxyphenyl)-6,6-dimethyl-4-oxo-2,3,4,5,6,7-hexahydrobenzofuran)-2,2'-(5,5-dimethylcyclohexane-1,3-dione)](1193375-04-0)
• EPA Substance Registry System: spiro[(3-(3-methoxyphenyl)-6,6-dimethyl-4-oxo-2,3,4,5,6,7-hexahydrobenzofuran)-2,2'-(5,5-dimethylcyclohexane-1,3-dione)](1193375-04-0)

Safety Data

• Hazardous Substances Data: 1193375-04-0(Hazardous Substances Data)

Upstream product

• 126-81-8 dimedone 
• 591-31-1 3-methoxy-benzaldehyde 

Relevant articles and documents

A pseudo multi-component electrochemical synthesis of spiro dihydrofuran derivatives

An electrochemical strategy to the assembly of tricyclic spiro dihydrofuran scaffold via the reaction of aryl aldehyde and dimedone has been developed successfully. This protocol has the advantages of high yields, wide application scope and an environmental benign procedure compared with the reported methods.

Synthesis of Spiro-dihydrofuran in the Presence of a Novel and Reusable Nanocatalyst Cu (II)-Glycerol/MCM-41

The use of supported Cu complex on mesoporous as a novel, efficient, heterogeneous, reusable and green catalyst for the synthesis of spiro-dihydrofuran derivatives is reported. This methodology is effective for the reaction of dimedone with a wide range of aldehyde in the presence of BrCN and triethylamine. The structure of catalyst was characterized by different techniques such as EDX, SEM, TGA, ICP-OES, XRD, TEM, FT-IR, and BET. The recycled nanocatalyst was used at least five times with no significant loss of its activity.

Selective formation of spiro dihydrofurans from one-pot reaction of dimedone with BrCN and aldehydes in the presence of Et3N

Reaction of 5,5-dimethylcyclohexane-1,3-dione (dimedone), aldehydes and cyanogen bromide in the presence of triethylamine leads to the selective formation of spiro dihydrofurans in moderate to good yields at room temperature.

Single-pot synthesis of spiroannulated dihydrofurans by iodine-ammonium acetate-mediated reaction of dimedone with aldehydes

Iodine-ammonium acetate-mediated annealation of dimedone with aldehydes led to facile formation of spirodihydrofuran in good yields through tandem Knoevenagel-Michael iodonation and cyclodehydroiodonation reactions in a single pot.