1193386-52-5 Usage
Uses
Used in Pharmaceutical Industry:
Ethyl 1-(5-chlorobenzo[d]oxazol-2-yl)piperidine-4-carboxylate is used as a potential pharmaceutical agent for various therapeutic applications due to its unique structural features. The benzooxazole ring and the ethyl ester functional group may contribute to its biological activity, making it a promising candidate for the development of new drugs.
In the development of new drugs, ethyl 1-(5-chlorobenzo[d]oxazol-2-yl)piperidine-4-carboxylate can be used as a lead compound for the design and synthesis of novel therapeutic agents. Its structural features can be further modified and optimized to enhance its pharmacological properties, such as potency, selectivity, and bioavailability.
Additionally, ethyl 1-(5-chlorobenzo[d]oxazol-2-yl)piperidine-4-carboxylate can be employed in the study of drug-target interactions, providing insights into the molecular mechanisms underlying its potential therapeutic effects. This knowledge can guide the rational design of more effective and safer drugs targeting specific diseases or conditions.
It is important to handle ethyl 1-(5-chlorobenzo[d]oxazol-2-yl)piperidine-4-carboxylate with care and to follow proper safety protocols when working with it in a laboratory setting. This ensures the safety of researchers and the integrity of the experimental results.
Check Digit Verification of cas no
The CAS Registry Mumber 1193386-52-5 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,1,9,3,3,8 and 6 respectively; the second part has 2 digits, 5 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 1193386-52:
(9*1)+(8*1)+(7*9)+(6*3)+(5*3)+(4*8)+(3*6)+(2*5)+(1*2)=175
175 % 10 = 5
So 1193386-52-5 is a valid CAS Registry Number.
1193386-52-5Relevant academic research and scientific papers
Novel benzoxazole inhibitors of mPGES-1
Kablaoui, Natasha,Patel, Snahel,Shao, Jay,Demian, Douglas,Hoffmaster, Keith,Berlioz, Francioise,Vazquez, Michael L.,Moore, William M.,Nugent, Richard A.
, p. 907 - 911 (2013/02/25)
A novel series of potent benzoxazole mPGES-1 inhibitors has been derived from a hit from a high throughput screen. Compound 37 displays mPGES-1 inhibition in an enzyme assay (0.018 μM) and PGE-2 inhibition in a cell-based assay (0.034 μM). It demonstrates 500- and 2500-fold selectivity for mPGES-1 over COX-2 and 6-keto PGF-1α, respectively. In vivo PK studies in dogs demonstrate 55% oral bioavailability and an 7 h half-life.
PIPERIDINECARBOXAMIDES AS MPGES - 1 INHIBITORS
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, (2011/07/09)
The invention relates to piperidinecarboxamides of formula (I), to their use in medicine as mPGES-1 inhibitors for the treatment of pain, to compositions containing them, to processes for their preparation and to intermediates used in such processes.
