1193386-52-5 Usage
General Description
Ethyl 1-(5-chlorobenzo[d]oxazol-2-yl)piperidine-4-carboxylate is a chemical compound with the molecular formula C16H18ClNO3. It is a piperidine derivative with a benzooxazole ring and an ethyl ester functional group. ethyl 1-(5-chlorobenzo[d]oxazol-2-yl)piperidine-4-carboxylate may have potential pharmaceutical applications due to its structural features. It is important to handle this chemical with care and to follow proper safety protocols when working with it in a laboratory setting.
Check Digit Verification of cas no
The CAS Registry Mumber 1193386-52-5 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,1,9,3,3,8 and 6 respectively; the second part has 2 digits, 5 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 1193386-52:
(9*1)+(8*1)+(7*9)+(6*3)+(5*3)+(4*8)+(3*6)+(2*5)+(1*2)=175
175 % 10 = 5
So 1193386-52-5 is a valid CAS Registry Number.
1193386-52-5Relevant articles and documents
Novel benzoxazole inhibitors of mPGES-1
Kablaoui, Natasha,Patel, Snahel,Shao, Jay,Demian, Douglas,Hoffmaster, Keith,Berlioz, Francioise,Vazquez, Michael L.,Moore, William M.,Nugent, Richard A.
, p. 907 - 911 (2013/02/25)
A novel series of potent benzoxazole mPGES-1 inhibitors has been derived from a hit from a high throughput screen. Compound 37 displays mPGES-1 inhibition in an enzyme assay (0.018 μM) and PGE-2 inhibition in a cell-based assay (0.034 μM). It demonstrates 500- and 2500-fold selectivity for mPGES-1 over COX-2 and 6-keto PGF-1α, respectively. In vivo PK studies in dogs demonstrate 55% oral bioavailability and an 7 h half-life.
