Welcome to LookChem.com Sign In|Join Free

CAS

  • or

119340-53-3

Post Buying Request

119340-53-3 Suppliers

Recommended suppliersmore

  • Product
  • FOB Price
  • Min.Order
  • Supply Ability
  • Supplier
  • Contact Supplier

119340-53-3 Usage

Uses

Cyclic adenosine diphosphate-ribose (cADPR) is an intracellular second messenger that mobilizes intracellular Ca2+ release from the sarcoplasmic reticulum through ryanodine receptors. CADPR is also a second messenger for glucose-induced insulin release from endocrine pancreas and for abscisic acid-induced calcium release in plants.

Definition

ChEBI: A cyclic purine nucleotide that is synthesised from NAD+ by ADP-ribosyl cyclase; acts as an agonist at ryanodine receptors.

Biochem/physiol Actions

Mobilizes intracellular Ca2+; regulates Ca2+-induced Ca2+?release specifically blocked by ryanodine; second messenger for glucose-induced insulin release from the endocrine pancreas and for abscisic acid-induced calcium release in plants.

Check Digit Verification of cas no

The CAS Registry Mumber 119340-53-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,1,9,3,4 and 0 respectively; the second part has 2 digits, 5 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 119340-53:
(8*1)+(7*1)+(6*9)+(5*3)+(4*4)+(3*0)+(2*5)+(1*3)=113
113 % 10 = 3
So 119340-53-3 is a valid CAS Registry Number.
InChI:InChI=1/C15H21N5O13P2/c16-12-7-13-18-4-19(12)14-10(23)8(21)5(31-14)1-29-34(25,26)33-35(27,28)30-2-6-9(22)11(24)15(32-6)20(13)3-17-7/h3-6,8-11,14-16,21-24H,1-2H2,(H,25,26)(H,27,28)/b16-12-/t5-,6-,8-,9-,10-,11-,14-,15-/m1/s1

119340-53-3SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name cyclic ADP-ribose

1.2 Other means of identification

Product number -
Other names cyclic adenosine 5'-diphosphoribose

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:119340-53-3 SDS

119340-53-3Downstream Products

119340-53-3Relevant articles and documents

Chemoenzymatic Synthesis of Analogues of the Second Messenger Candidate Cyclic Adenosine 5'-Diphosphate Ribose

Ashamu, Gloria A.,Galione, Antony,Potter, Barry V. L.

, p. 1359 - 1360 (1995)

A broad substrate specificity for adenosine 5'-diphosphate ribosyl cyclase is demonstrated by cyclisation of ribose- and purine-modified nicotinamide adenine dinucleotide analogues to mimics of cyclic adenosine 5'-diphosphate ribose, generating a straightforward route for structural modification of this important Ca2+ -mobilising nucleotide.

cADPR Analogues: Effect of an Adenosine 2′- Or 3′-Methoxy Group on Conformation

Graham, Steven M.,Macaya, Daniel J.,Sengupta, Raghuvir N.,Turner, Kevin B.

, p. 233 - 236 (2004)

(Matrix presented) The 2′-OMe-A (2) and 3′-OMe-A (3) analogues of the calcium release agent cADPR (1) were prepared and their solution structures studied by NMR spectroscopy. Compared to 1, 2 shows a shift in its A ring conformation and changes in its R ring N:S and γt: γ+ ratios, while 3 displays a significant change in the conformation of its A ring γ-bond.

Post a RFQ

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

1

What can I do for you?
Get Best Price

Get Best Price for 119340-53-3