119349-57-4

Basic information

• Product Name: Dl-3-Phenoxyphenylalanine
• Synonyms: 3-Phenoxy-DL-phenylalanine
• CAS NO: 119349-57-4
• Molecular Formula: C15H15NO3
• Molecular Weight: 257.28
• Mol File: 119349-57-4.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Dl-3-Phenoxyphenylalanine(CAS DataBase Reference)
• NIST Chemistry Reference: Dl-3-Phenoxyphenylalanine(119349-57-4)
• EPA Substance Registry System: Dl-3-Phenoxyphenylalanine(119349-57-4)

Safety Data

• Hazardous Substances Data: 119349-57-4(Hazardous Substances Data)

Usage

General Description

Dl-3-Phenoxyphenylalanine is a chemical compound consisting of a phenylalanine molecule with a phenoxy group attached to the 3-position. It is a non-natural amino acid derivative that has been used in the synthesis of various peptides and peptidomimetics for pharmaceutical and biochemical research. Dl-3-Phenoxyphenylalanine may also have potential applications in the development of new drugs due to its unique chemical structure and properties. Its synthesis and study have contributed to the understanding of organic chemistry and amino acid derivatives, leading to potential advancements in the field of medicinal chemistry.

Relevant articles and documents

Phenylalanine derivative and proteinase inhibitor

A phenylalanine derivative having the formula (I): STR1 wherein A represents STR2 B represents STR3 wherein m is 0, 1, or 2 and n is 3, 4, or 5; X represents (a) hydroxy, (b) nitro, (c) amino, (d) phenoxy which may be substituted with (i) halogen or (ii) nitro, (e) c1 -C4 alkyloxy which may be substituted wit (i) phenyl or (ii) benzoyl, (f) benzoyl, (g) pyridyloxy which may be substituted with (i) halogen or (ii) nitro, or (h) c1 -C4 alkyl which may by substituted with halogen; Y represents STR4 or --OR3 wherein R1 R2 are independently (a) hydrogen, (b) phenyl which may be substituted with (i) benzoyl, (ii) C1 -C4 alkylcarbonyl, (iii) C1 -C4 alkyl which may be further substituted with C1 -C4 alkoxycarbonyl or hydroxycarbonyl, (iv) C2 -C5 alkenyl which may be further substituted with hydroxycarbonyl or C1 -C4 alkoxycarbonyl, (v) C1 -C4 alkoxycarbonyl, or (vi) amidino, (c) pyridyl which may be substituted with halogen or carboxyl (d) imidazolyl, (e) pyrimidyl, (f) tetrazolyl, (g) thiazolyl which may be substituted with C1 -C4 alkyl which may be further substituted with C1 -C4 alkoxycarbonyl, (h) C1 -C6 alkyl which may be substituted with C1 -C4 alkoxy, C1 -C4 alkoxycarbonyl, phenyl, or benzoyl, (i) C5 -C7 cycloalkyl which may be substituted with C1 -C4 alkoxycarbonyl or (j) R1 and R2 may form, with the nitrogen atom attached thereto, (i) pyperazyl which may be substituted on the nitrogen atom with C1 -C4 alkyl which may be further substituted with phenyl, (ii) piperidino which may be substituted with carboxyl or C1 -C4 alkoxycarbonyl, (iii) pyrrolidyl which may be substituted with C1 -C4 alkoxycarbonyl, or (iv) morpholyl; and R3 represents (a) hydrogen, (b) C1 -C6 alkyl which may be substituted with (i) C1 -C4 alkoxy, (ii) pehnyl, or (iii) pyridyl, or (c) pyridyl; or a pharmaceutically acceptable acid salt thereof. This phenylalanine derivative is effective as a proteinase.