119350-41-3Relevant academic research and scientific papers
Chiral-Organotin-Catalyzed Kinetic Resolution of Vicinal Amino Alcohols
Yang, Hui,Zheng, Wen-Hua
supporting information, p. 16177 - 16180 (2019/11/03)
A highly efficient kinetic resolution of racemic amino alcohols has been achieved for the first time with a chiral tin catalyst. A chiral organotin compound with 3,4,5-trifluorophenyl groups at the 3,3′-positions of the binaphthyl framework enabled this transformation with excellent yield and high enantioselectivity. The process tolerates aryl- and alkyl-substituted amino alcohols and a variety of other substrates, affording the corresponding products in high enantioselectivity and with s factors up to >500.
3,5-Bis(n-perfluorooctyl)benzyltriethylammonium bromide (F-TEBA): An efficient, easily recoverable fluorous catalyst for solid-liquid PTC reactions
Pozzi, Gianluca,Mihali, Voichita,Foschi, Francesca,Penso, Michele,Quici, Silvio,Fish, Richard H.
supporting information; experimental part, p. 3072 - 3076 (2010/04/06)
A readily available 3,5-bis(perfluorooctyl)benzyl bromide and triethylamine were reacted under mild conditions to give 3,5-bis(n-perfluorooctyl) benzyltriethylammonium bromide (F-TEBA), an analogue of the versatile phase-transfer catalyst, benzyltriethyla
Synthesis of 2,6-disubstituted morpholines through regioselective oxiranes ring opening by tosylamide under PTC conditions
Lupi, Vittoria,Albanese, Domenico,Landini, Dario,Scaletti, Davide,Penso, Michele
, p. 11709 - 11718 (2007/10/03)
Symmetric and non-symmetric 2,6-disubstituted morpholines were synthesized through regioselective nucleophilic ring opening of oxiranes with tosylamide under solid-liquid phase transfer catalysis (SL-PTC) conditions followed by cyclization of the tosylami
Synthesis of N-sulfonyl aziridines through regioselective opening of epoxides under solid-liquid PTC conditions
Albanese, Domenico,Landini, Dario,Penso, Michele,Petricci, Silvia
, p. 6387 - 6394 (2007/10/03)
The ring opening of epoxides 1 with 4-toluenesulfonamide (6) under solid-liquid phase transfer catalysis (SL-PTC) conditions afforded regioselectively β-sulfonamidoalcohols 7 in high yields. These were further convened into N-sulfonylaziridines 9 after ac
Chemistry of Sulfonyl Isocyanates and Sulfonyl Isothiocyanates. XI. Cyclizations with Epoxides
McFarland, J. W.,Beaulieu, J. J.,Arrey, L. N.,Frey, L. M.
, p. 1431 - 1434 (2007/10/02)
4-Toluenesulfonyl isocyanate cyclized with 1,2-epoxy-3-phenoxypropane and 2,3-epoxypropyl 4-methoxyphenyl ether, respectively, to give 3-(4-toluenesulfonyl)-5-phenoxymethylene-2-oxazolidone (I) and 3-(4-toluenesulfonyl)-5-(4-methoxyphenoxymethylene)-2-oxazolidone (II).Compounds I and II were hydrolyzed in 2 M sodium hydroxide solution to the corresponding uncyclized hydroxy amides, VII and VIII.Compound I was remarkably stable toward 6M hydrochloric acid and amines.Styrene oxide, 1,2-epoxybutane, 3-chloro-1,2-epoxypropane, and 1-methoxy-2-methylpropylene oxide reacted with the isocyanate to afford 3-(4-toluenesulfonyl)-4-phenyl-2-oxazolidone (III), 3-(4-toluenesulfonyl)-4-ethyl-2-oxazolidone (IV), 3-(4-toluenesulfonyl)-5-chloromethyl-2-oxazolidone (V), and 3-(4-toluenesulfonyl)-4,4-dimethyl-5-methoxy-2-oxazolidone (VI), respectively.The yield of VI was constant over a temperature range of 25-90 deg.
