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MAChR-IN-1 is a chemical compound that functions as a positive allosteric modulator of the muscarinic acetylcholine receptor M1. It exhibits high selectivity for M1 receptors, thereby enhancing the binding of acetylcholine at these sites. The modulation of M1 receptor activity by MAChR-IN-1 holds potential therapeutic significance, particularly in the treatment of neurodegenerative diseases, given the involvement of M1 receptors in cognitive function and memory processes. MAChR-IN-1 is also valuable for investigating the specific role of M1 receptors in neurological disorders and for the development of new treatments that target these receptors. Further research is necessary to fully elucidate the pharmacological characteristics and therapeutic potential of MAChR-IN-1.

119391-56-9

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119391-56-9 Usage

Uses

Used in Pharmaceutical Industry:
MAChR-IN-1 is used as a therapeutic agent for the treatment of neurodegenerative diseases, leveraging its ability to modulate M1 receptor activity, which is implicated in cognitive function and memory processes.
Used in Research and Development:
MAChR-IN-1 is used as a research tool for studying the specific role of M1 receptors in neurological disorders, aiding in the understanding of the receptor's function and its potential as a target for novel treatments.
Used in Drug Discovery:
MAChR-IN-1 serves as a lead compound in the development of new pharmaceuticals targeting M1 receptors, potentially leading to the creation of innovative treatments for neurodegenerative conditions.

Check Digit Verification of cas no

The CAS Registry Mumber 119391-56-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,1,9,3,9 and 1 respectively; the second part has 2 digits, 5 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 119391-56:
(8*1)+(7*1)+(6*9)+(5*3)+(4*9)+(3*1)+(2*5)+(1*6)=139
139 % 10 = 9
So 119391-56-9 is a valid CAS Registry Number.

119391-56-9Downstream Products

119391-56-9Relevant academic research and scientific papers

Synthesis and biological evaluation of [125I]- and [123I]-4-iododexetimide, a potent muscarinic cholinergic receptor antagonist

Wilson,Dannals,Ravert,Frost,Wagner Jr.

, p. 1057 - 1062 (2007/10/02)

A series of halogenated racemic analogues of dexetimide (1) was synthesized and their affinity for the muscarinic cholinergic receptor measured. One analogue, 4-iododexetimide (21), was efficiently labeled with 125I and 123I at high

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