119392-95-9

Usage

Uses

Used in Chemical Synthesis:
(R)-(+)-N,N-DIMETHYL-1-(1-NAPHTHYL)ETHYLAMINE is used as a reactant in the formation of cyclopalladated naphthyl adducts. The compound reacts with palladium acetate in acetic acid, which is significant for the development of new chemical compounds and materials with potential applications in various industries.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, (R)-(+)-N,N-DIMETHYL-1-(1-NAPHTHYL)ETHYLAMINE may be used as a building block or intermediate in the synthesis of various drugs and medicinal compounds. Its unique structure and reactivity can be exploited to create new molecules with specific therapeutic properties.
Used in Material Science:
(R)-(+)-N,N-DIMETHYL-1-(1-NAPHTHYL)ETHYLAMINE could also be utilized in the field of material science, where it may contribute to the development of novel materials with specific properties, such as improved conductivity, stability, or optical characteristics.

InChI:InChI=1/C14H17N/c1-11(15(2)3)13-10-6-8-12-7-4-5-9-14(12)13/h4-11H,1-3H3/t11-/m1/s1

Upstream product

• 50-00-0 formaldehyd 
• 3886-70-2 (R)-1-(1-Naphthyl)ethylamine 
• 10420-89-0 (S)-1-(1-Naphthyl)ethylamine 
• 86926-16-1 N,N-dimethyl[1-(1-naphthyl)ethyl]amine 

Downstream Products

• 1416982-06-3 (S)-1-(1-p-tolylethyl)naphthalene 
• 941-98-0 1'-naphthacetophenone 
• 80145-77-3 bis(μ-chloro)bis[(R)-2-[1-(dimethylamino)ethyl]-naphthyl-C,N]dipalladium(II) 

Relevant academic research and scientific papers

Cu2O-catalyzed C–S coupling of quaternary ammonium salts and sodium alkane-/arene-sulfinates

A new protocol for the synthesis of (enantioenriched) benzylic sulfones via the Cu2O-catalyzed C–S bond cross coupling of alkane-/arene-sulfinates and (enantioenriched) benzylic quaternary ammonium salts has been developed. The product benzylic sulfones were obtained in good to high yields (75–96%). Chiral arylmethyl sulfones with high enantiomeric excess (90–94% ee) were also synthesized in the presence of Cu2O and 1,1′-bis-(diphenylphosphino)ferrocene (dppf).

Asymmetric induction in the arenethiolatocopper(I)-catalyzed substitution reaction of Grignard reagents with allylic substrates

The influence of some experimental parameters on the regio- and enantioselectivity in the 'γ-selective substitution reaction of Grignard reagents RMgX with acyclic allylic acetates catalyzed by the arenethiolatocopper(I) complex (S)-1 was studied. When more bulky arenethiolatocopper(I) complexes than (S)-1 were employed in a reaction of allylic acetate 3 with n-BuMgI, the enantioselectivities observed for the γ- product were lower. With an arenethiolatocopper(I) catalyst prepared in situ, several Grignard reagents were studied in a substitution reaction with acetate 2. Compared to n-BuMgI, more bulky Grignard reagents gave no improvement of the enantioselectivity in the formation of the γ-product. (C) 2000 Elsevier Science Ltd.

PHOSPHORORGANISCHE VERBINDUNGEN 102. TERTIAERE PHOSPHINE MIT o-DIALKYLAMINOPHENYL- UND ORTHO-DIALKYLAMINOBENZYLGRUPPEN

N,N-dialkylarylamines and N,N-dialkylbenzylamines are lithiated with n-butyllithium (n-BuLi) under the assistance of tetramethylethylenediamine (TMEDA) in the ortho-position.According the Eqs. (1) and (4) triarylphosphines (30-50percent) are obtained. 1-(N,N-dimethylamino)-naphthalene and N,N-dimethyl-1-(1-naphthyl)-ethylamine 18 are lithiated in the 8-position.In N,N-dimethyl-1-(2-naphthyl)-ethylamine 19 the 1- and 3-position is lithiated in nearly equal amount.Experiments to introduce lithium twice into the model compounds 28-30 are without success.