1194045-65-2Relevant academic research and scientific papers
μ-Opioid/5-HT4 dual pharmacologically active agents-Efforts towards an effective opioid analgesic with less GI and respiratory side effects (Part I)
Shao, Liming,Wang, Fengjiang,Hewitt, Michael C.,Barberich, Timothy J.
scheme or table, p. 5679 - 5683 (2010/04/26)
Novel compounds were prepared that united the pharmacologies of the μ-opioid tramadol with the 5-HT4 agonists metoclopramide and norcisapride. The synthesis, chiral separation and in vitro activity of the new compounds is described.
