1194055-09-8

Basic information

• Product Name: 1-(5-chloro-pyridin-2-yl)-5-methyl-1H-pyrazole-4-carboxylic acid [(S)-1-(3-trifluoromethyl-phenyl)-ethyl]-amide
• Synonyms: 1-(5-chloro-pyridin-2-yl)-5-methyl-1H-pyrazole-4-carboxylic acid [(S)-1-(3-trifluoromethyl-phenyl)-ethyl]-amide
• CAS NO: 1194055-09-8
• Molecular Weight: 408.81
• Mol File: 1194055-09-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1-(5-chloro-pyridin-2-yl)-5-methyl-1H-pyrazole-4-carboxylic acid [(S)-1-(3-trifluoromethyl-phenyl)-ethyl]-amide(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(5-chloro-pyridin-2-yl)-5-methyl-1H-pyrazole-4-carboxylic acid [(S)-1-(3-trifluoromethyl-phenyl)-ethyl]-amide(1194055-09-8)
• EPA Substance Registry System: 1-(5-chloro-pyridin-2-yl)-5-methyl-1H-pyrazole-4-carboxylic acid [(S)-1-(3-trifluoromethyl-phenyl)-ethyl]-amide(1194055-09-8)

Safety Data

• Hazardous Substances Data: 1194055-09-8(Hazardous Substances Data)

Upstream product

• 40704-11-8 5-methyl-1H-pyrazole-4-carboxylic acid 
• 1194056-10-4 5-methyl-1H-pyrazole-4-carboxylic acid [(S)-1-(3-trifluoromethyl-phenyl)-ethyl]-amide 
• 244221-57-6 5-chloro-2-iodo-pyridine 

Relevant articles and documents

PYRAZOLE COMPOUNDS AS CCR1 ANTAGONISTS

Disclosed are compounds of the formula I which block the interaction of CCR1 and its ligands and are thus useful for treating a variety of diseases and disorders that are mediated or sustained through the activity of CCR1 including autoimmune diseases, such as rheumatoid arthritis and multiple sclerosis. Also disclosed are pharmaceutical compositions comprising these compounds, methods of using these compounds in the treatment of various diseases and disorders, processes for preparing these compounds and intermediates useful in these processes.