1194061-01-2Relevant academic research and scientific papers
Structure-activity studies on seco-pancratistatin analogs: Potent inhibitors of human cytochrome P450 3A4
McNulty, James,Nair, Jerald J.,Singh, Mohini,Crankshaw, Denis J.,Holloway, Alison C.
scheme or table, p. 5607 - 5612 (2010/04/30)
Two total syntheses of fully functionalized seco-analogs of the anticancer compound pancratistatin are reported. Structure-activity relationship (SAR) studies identified potent and selective inhibitors of human cytochrome P450 3A4 (CYP3A4) and revealed se
