1194244-49-9Relevant articles and documents
Asymmetric synthesis of γ-chiral borylalkanes: Via sequential reduction/hydroboration using a single copper catalyst
Han, Jung Tae,Lee, Jin Yong,Yun, Jaesook
, p. 8961 - 8965 (2020)
The synthesis of γ-chiral borylalkanes through copper-catalyzed enantioselective SN2′-reduction of γ,γ-disubstituted allylic substrates and subsequent hydroboration was reported. A copper-DTBM-Segphos catalyst produced a range of γ-chiral alkylboronates from easily accessible allylic acetate or benzoate with high enantioselectivities up to 99% ee. Furthermore, selective organic transformations of the resulting γ-chiral alkylboronates generated the corresponding γ-chiral alcohol, arene and amine compounds.
Zn-mediated, Pd-catalyzed cross-couplings in water at room temperature without prior formation of organozinc reagents
Krasovskiy, Arkady,Duplais, Christophe,Lipshutz, Bruce H.
supporting information; experimental part, p. 15592 - 15593 (2010/01/30)
(Chemical Equation Presented) Mix in water, stir. That is all that is required in this new approach to sp3-sp2 cross-couplings between an alkyl iodide and an aryl bromide, both potentially bearing functionality. They react under cata
