1194377-09-7 Usage
General Description
4-Iodo-1-methyl-3-trifluoromethyl-1H-pyrazole is a chemical compound with the molecular formula C6H5F3IN2. It is a pyrazole derivative that contains an iodine atom, a methyl group, and a trifluoromethyl group attached to the pyrazole ring. 4-Iodo-1-methyl-3-trifluoromethyl-1H-pyrazole has potential applications in pharmaceutical and agrochemical industries, as it can be used as a building block in the synthesis of organic compounds with biological activity. Its specific properties and potential uses are still under investigation, but its unique structure and functional groups make it an interesting target for chemical research and development.
Check Digit Verification of cas no
The CAS Registry Mumber 1194377-09-7 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,1,9,4,3,7 and 7 respectively; the second part has 2 digits, 0 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 1194377-09:
(9*1)+(8*1)+(7*9)+(6*4)+(5*3)+(4*7)+(3*7)+(2*0)+(1*9)=177
177 % 10 = 7
So 1194377-09-7 is a valid CAS Registry Number.
1194377-09-7Relevant articles and documents
Structure-based design of orally bioavailable 1 h -Pyrrolo[3,2- C ]pyridine inhibitors of mitotic kinase monopolar spindle 1 (MPS1)
Naud, Sébastien,Westwood, Isaac M.,Faisal, Amir,Sheldrake, Peter,Bavetsias, Vassilios,Atrash, Butrus,Cheung, Kwai-Ming J.,Liu, Manjuan,Hayes, Angela,Schmitt, Jessica,Wood, Amy,Choi, Vanessa,Boxall, Kathy,Mak, Grace,Gurden, Mark,Valenti, Melanie,De Haven Brandon, Alexis,Henley, Alan,Baker, Ross,McAndrew, Craig,Matijssen, Berry,Burke, Rosemary,Hoelder, Swen,Eccles, Suzanne A.,Raynaud, Florence I.,Linardopoulos, Spiros,Van Montfort, Rob L. M.,Blagg, Julian
supporting information, p. 10045 - 10065 (2014/01/17)
The protein kinase MPS1 is a crucial component of the spindle assembly checkpoint signal and is aberrantly overexpressed in many human cancers. MPS1 is one of the top 25 genes overexpressed in tumors with chromosomal instability and aneuploidy. PTEN-defic
