1194454-59-5Relevant academic research and scientific papers
Dendrimers in solution can have their remote catalytic groups folded back into the core: Enantioselective transaminations by dendritic enzyme mimics-II
Wei, Sujun,Wang, Jianing,Venhuizen, Scott,Skouta, Rachid,Breslow, Ronald
, p. 5543 - 5546 (2009)
PAMAM dendrimers with double thioether arms have been synthesized with a pyridoxamine core and terminal chiral amino groups. Transamination to afford natural isomers of phenylalanine and alanine induced enantioselectivity by the peripheral chiral caps, supporting a computer model that indicates folding of dendrimer chains back into the core.
