1194565-82-6Relevant articles and documents
Comparative molecular field analysis and synthetic validation of a hydroxyamide-propofol binding and functional block of neuronal voltage-dependent sodium channels
Brown, Milton L.,Eidam, Hilary A.,Paige, Mikell,Jones, Paulianda J.,Patel, Manoj K.
experimental part, p. 7056 - 7063 (2009/12/24)
Voltage gated sodium channels represent an important therapeutic target for a number of neurological disorders including epilepsy. Unfortunately, medicinal chemistry strategies for discovering new classes of antagonist for trans-membrane ion channels have