119461-45-9

Upstream product

• 119461-44-8 ((Z)-(S)-1-Methyl-4-trimethylsilanyl-but-3-enyl)-[1-phenyl-meth-(E)-ylidene]-amine 
• 119461-42-6 (S)-N-(p-toluenesulfonyl)-4-amino-1-Z-(trimethylsilyl)-1-pentene 
• 119461-41-5 (S)-N-(p-toluenesulfonyl)-4-amino-1-(trimethylsilyl)-1-pentyne 
• 119461-43-7 (S)-4-amino-1-(trimethylsilyl)-1-pentyne 

Downstream Products

• 119461-54-0 rac-trans-N-(ethoxycarbonyl)-6-methyl-2-phenyl-1,2,5,6-tetrahydropyridine 
• 119461-49-3 rac-trans-N-benzyl-6-methyl-2-phenyl-1,2,5,6-tetrahydropyridine 
• 119461-54-0 rac-cis-N-(ethoxycarbonyl)-6-methyl-2-phenyl-1,2,5,6-tetrahydropyridine 
• 119461-52-8 rac-trans-N-methyl-6-methyl-2-phenyl-1,2,5,6-tetrahydropyridine 

Relevant academic research and scientific papers

SYNTHESIS OF SUBSTITUTED TETRAHYDROPYRIDINES BY CYCLIZATIONS OF SILICON-CONTAINING IMINIUM IONS

Trans-2,6-disubstituted-1,2,5,6-tetrahydropyridines are formed stereoselectively from the cyclization of silicon-containing iminium cations 5 if the nitrogen substituents R1 is an alkyl group.In contrast, cyclization of the corresponding NH or N-acyl iminium ions occurs in a stereorandom fashion.Nonracemic tetrahydropyridines cannot be prepared in this way, since both iminium ion and N-acyliminium ion intermediates racemize prior to cyclization.