1194975-46-6

Upstream product

• 24424-99-5 di-tert-butyl dicarbonate 
• 1188405-50-6 C₁₂H₁₈N₂O₂ 
• 501-53-1 benzyl chloroformate 
• 1194973-92-6 (R)-benzyl (1-amino-1-oxobutan-2-yl)carbamate 

Downstream Products

• 1194975-22-8 C₉H₂₀N₂O₂ 
• 1374969-75-1 C₂₃H₂₉FN₈O₃ 

Relevant academic research and scientific papers

BENZAMIDES AND NICOTINAMIDES AS SYK MODULATORS

The present invention is directed to compounds of formula I and pharmaceutically acceptable salts, esters, and prodrugs thereof which are inhibitors of Syk kinase. The present invention is also directed to intermediates used in making such compounds, the preparation of such a compound, pharmaceutical compositions containing such a compound, methods of inhibition Syk kinase activity, methods of inhibition the platelet aggregation, and methods to prevent or treat a number of conditions mediated at least in part by Syk kinase activity, such as Non Hodgkin's Lymphoma.