1195-25-1Relevant articles and documents
TREATMENT OF DISEASES BY EPIGENETIC REGULATION
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Paragraph 0501; 0502, (2013/11/05)
The present disclosure provides non-naturally occurring polyphenol compounds that inhibit the bromodomain and extra terminal domain (BET) proteins. The disclosed compositions and methods can be used for treatment and prevention of diseases or disorders that are susceptible to administration of a BET inhibitor.
QUINOLINE DERIVATIVES
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Page/Page column 105, (2008/06/13)
The invention concerns quinoline derivatives of Formula (I): or a pharmaceutically-acceptable salt thereof, wherein each of X1, p, R1, q, R2, R3, R4, R5, Ring A, r and R6 has any of the meanings defined hereinbefore in the description; processes for their preparation, pharmaceutical compositions containing them and their use in the manufacture of a medicament for use in the treatment of cell proliferative disorders.
3-Substituted-1,2,4-Oxadiazolin-5-one; A Useful Amidine Precursor and Protecting Group
Bolton, Richard E.,Coote, Steven J.,Finch, Harry,Lowdon, Andrew,Pegg, Neil,Vinader, M. Victoria
, p. 4471 - 4474 (2007/10/02)
5-Benzyloxy-1,2,4-oxadiazoles and 1,2,4-oxadiazolin-5-ones are useful precursors to, and protecting groups for the amidine moiety.The latter compounds are readily prepared from amidoximes or alternatively via cycloaddition of nitrile oxides to trichloroac