1195-25-1

Usage

Uses

Used in Pharmaceutical Industry:
4-Chloro-3-fluoro-2-Methylpyridine is used as an intermediate in the production of various pharmaceuticals for its ability to serve as a building block in the synthesis of functional materials, contributing to the development of new drugs and therapeutic agents.
Used in Agrochemical Industry:
In the agrochemical industry, 4-Chloro-3-fluoro-2-Methylpyridine is used as an intermediate in the synthesis of various agrochemicals, including insecticides, due to its reactive nature and potential to form compounds with pesticidal properties.
Used in Dye and Pigment Production:
4-Chloro-3-fluoro-2-Methylpyridine is used as a building block in the manufacturing of dyes and pigments, where its chemical properties allow for the creation of a variety of colorants for different applications.
Used in Chemical Product Creation:
4-Chloro-3-fluoro-2-Methylpyridine's chemical properties make it suitable for use in the creation of a variety of chemical products, including those in research and development, where its reactivity and structural features can be leveraged to produce novel compounds with specific functions or properties.

InChI:InChI=1/C4H3Cl3N2O/c1-2-8-3(10-9-2)4(5,6)7/h1H3

Upstream product

• 118493-85-9 acetamide oxime 
• 4124-31-6 trichloroacetic acid anhydride 
• 79-24-3 Nitroethane 
• 103-71-9 phenyl isocyanate 
• 545-06-2 trichloroacetonitrile 

Downstream Products

• 19703-92-5 5-methyl-[1,2,4]oxadiazole-3-carboxylic acid 
• 167773-20-8 5-benzyloxy-3-methyl-1,2,4-oxadiazole 
• 3663-39-6 3-methyl-5-amino-1,2,4-oxadiazole 
• 1253732-82-9 2-{3,5-dimethyl-4-[2-(3-methyl[1,2,4]oxadiazol-5-ylamino)ethoxy]phenyl}-5,7-dimethoxy-3H-quinazolin-4-one 
• 1193-78-8 5-dichloromethyl-3-methyl-1,2,4-oxadiazole 
• 103-19-5 di(p-tolyl) disulfide 

Relevant academic research and scientific papers

TREATMENT OF DISEASES BY EPIGENETIC REGULATION

The present disclosure provides non-naturally occurring polyphenol compounds that inhibit the bromodomain and extra terminal domain (BET) proteins. The disclosed compositions and methods can be used for treatment and prevention of diseases or disorders that are susceptible to administration of a BET inhibitor.

NOVEL ANTI-INFLAMMATORY AGENTS

Disclosed are methods of regulating interleukin-6 (IL-6) and/or vascular cell adhesion molecule-1 (VCAM-1) and methods of treating and/or preventing cardiovascular and inflammatory diseases and related disease states, such as, for example, atherosclerosis, asthma, arthritis, cancer, multiple sclerosis, psoriasis, and inflammatory bowel diseases, and autoimmune disease(s) by administering a naturally occurring or synthetic quinazolone derivative. The invention provides novel synthetic quinazolone compounds, as well as pharmaceutical compositions comprising those compounds.

QUINOLINE DERIVATIVES

The invention concerns quinoline derivatives of Formula (I): or a pharmaceutically-acceptable salt thereof, wherein each of X1, p, R1, q, R2, R3, R4, R5, Ring A, r and R6 has any of the meanings defined hereinbefore in the description; processes for their preparation, pharmaceutical compositions containing them and their use in the manufacture of a medicament for use in the treatment of cell proliferative disorders.

(R,R) AND (S,S) 2,5-DIAZABICYCLO [2,2,1]HEPTANE DERIVATIVES

Compounds of the Formulae I or II STR1 wherein Z and R 1, are as described herein which compounds are muscarinic agonists useful in treating central cholinergic disfunction and pharmaceutical compositions containing the compounds.

3-Substituted-1,2,4-Oxadiazolin-5-one; A Useful Amidine Precursor and Protecting Group

5-Benzyloxy-1,2,4-oxadiazoles and 1,2,4-oxadiazolin-5-ones are useful precursors to, and protecting groups for the amidine moiety.The latter compounds are readily prepared from amidoximes or alternatively via cycloaddition of nitrile oxides to trichloroac