1195-34-2

Usage

Uses

Used in Pharmaceutical Industry:
4,6-Dichloro-2-ethylpyrimidine is used as a chemical intermediate for the synthesis of various pharmaceuticals. Its unique molecular structure allows it to be incorporated into the development of new drugs, potentially leading to the creation of novel therapeutic agents.
Used in Agrochemical Industry:
In the agrochemical sector, 4,6-Dichloro-2-ethylpyrimidine serves as a key intermediate in the production of various agrochemicals. Its incorporation into these products can contribute to the development of more effective and targeted pest control solutions, enhancing agricultural productivity and crop protection.

Upstream product

• 857411-92-8 2-ethyl-1H-pyrimidine-4,6-dione 
• 7732-18-5 water 
• 925-90-6 ethylmagnesium bromide 
• 4489-34-3 4,6-dichloro-2-(methylsulfonyl)pyrimidine 
• 3709-98-6 2-ethylpyrimidine-4,6-diol 

Downstream Products

• 94415-35-7 4-chloro-2-ethyl-6-hydrazinylpyrimidine 

Relevant academic research and scientific papers

PYRIMIDINONE DERIVATIVE HAVING AUTOTAXIN-INHIBITORY ACTIVITY

A compound according to any one of formula (Ia) to (Ic), or its pharmaceutically acceptable salt: wherein R1, R2, R3, R4a, R4c, R5 are as defined in the description.

PYRIMIDINE PDE10 INHIBITORS

The present invention is directed to pyrimidine compounds which are useful as therapeutic agents for the treatment of central nervous system disorders associated with phosphodiesterase 10 (PDE10). The present invention also relates to the use of such compounds for treating neurological and psychiatric disorders, such as schizophrenia, psychosis or Huntington's disease, and those associated with striatal hypofunction or basal ganglia dysfunction.

PREVENTIVES OR REMEDIES FOR ALZHEIMER'S DISEASE OR AMYLOID PROTEIN FIBROSIS INHIBITORS CONTAINING NITROGEN-CONTAINING HETEROARYL COMPOUNDS

The present invention relates to preventives or remedies for Alzheimer's disease, or to amyloid protein fibril-formation inhibitors, which include as an active ingredient a compound of general formula (I) below or a pharmacologically permitted salt thereo

Pyrimidines substituted by nitrogen-containing heterocyclic rings as intermediates

1,2,4-Triazolo[4,3-c]pyrimidines substituted at the 5 or 7 position through a nitrogen atom which is part of a heterocyclic ring have been found to have potent bronchodilator activity and to be useful synthetic intermediates in the preparation of 1,2,4-triazolo[1,5-c]pyrimidines. Methods for inducing bronchodilation, pharmaceutical compositions, and synthetic processes and intermediates are also described.

Triazolo [4,3-c]pyrimidines substituted by nitrogen-containing heterocyclic rings

1,2,4-Triazolo[4,3-c]pyrimidines substituted at the 5 or 7 position through a nitrogen atom which is part of a heterocyclic ring have been found to have potent bronchodilator activity and to be useful synthetic intermediates in the preparation of 1,2,4-triazolo[1,5-c]-pyrimidines. Methods for inducing bronchodilation, pharmaceutical compositions, and synthetic processes and intermediates are also described.