1195-58-0

Basic information

• Product Name: 3,5-DICYANO PYRIDINE
• Synonyms: 3,5-PYRIDINEDICARBONITRILE;3,5-DICYANO PYRIDINE;35DCPY;pyridine-3,5-dicarbonitrile;3,5-Pyridinedicarbonitrile(6CI,7CI,8CI,9CI)
• CAS NO: 1195-58-0
• Molecular Formula: C₇H₃N₃
• Molecular Weight: 129.12
• EINECS: 214-802-5
• Product Categories: PYRIDINE
• Mol File: 1195-58-0.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 247.5°Cat760mmHg
• Flash Point: 96.4°C
• Appearance: /
• Density: 1.25g/cm³
• Vapor Pressure: 0.0255mmHg at 25°C
• Refractive Index: 1.567
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: 3,5-DICYANO PYRIDINE(CAS DataBase Reference)
• NIST Chemistry Reference: 3,5-DICYANO PYRIDINE(1195-58-0)
• EPA Substance Registry System: 3,5-DICYANO PYRIDINE(1195-58-0)

Safety Data

• Hazardous Substances Data: 1195-58-0(Hazardous Substances Data)

Usage

General Description

3,5-Dicyano pyridine is a chemical compound with the molecular formula C7H3N3. It is a colorless to light yellow crystalline solid that is used in organic synthesis and as a building block for the preparation of various pharmaceuticals and agrochemicals. 3,5-dicyano pyridine is a versatile reagent with a variety of applications including in the synthesis of heterocycles, dyes, and pharmaceuticals. It is also used as a ligand in coordination chemistry and as a catalyst in various reactions. Additionally, it is an important intermediate in the production of pesticides and can be used as a precursor in the manufacturing of 3-cyano pyridine, a compound used in the synthesis of vitamin B6.

InChI:InChI=1/C7H3N3/c8-2-6-1-7(3-9)5-10-4-6/h1,4-5H

Upstream product

• 557-21-1 zinc(II) cyanide 
• 2457-47-8 3,5-dichloropyridine 
• 499-81-0 3,5-Pyridinedicarboxylic acid 
• 591-22-0 3,5-Lutidine 
• 1539-48-6 2,4,6-trimethylpyridine-3,5-dicarbonitrile 
• 4663-99-4 pyridine-3,5-dicarboxamide 

Downstream Products

• 280-74-0 3,7-diazabicyclo{3.3.1}nonane 
• 146073-63-4 2,6-di(1-adamantyl)pyridine-3,5-dicarbonitrile 
• 146073-61-2 2-isopropylpyridine-3,5-dicarbonitrile 
• 1221430-89-2 5-(4-amino-6-benzyl-thieno[2,3-d]pyrimidin-2-yl)nicotinonitrile 

Relevant articles and documents

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General and Mild Nickel-Catalyzed Cyanation of Aryl/Heteroaryl Chlorides with Zn(CN)2: Key Roles of DMAP

A new and general nickel-catalyzed cyanation of hetero(aryl) chlorides using less toxic Zn(CN)2 as the cyanide source has been developed. The reaction relies on the use of inexpensive NiCl2·6H2O/dppf/Zn as the catalytic system and DMAP as the additive, allowing the cyanation to occur under mild reaction conditions (50-80 °C) with wide functional group tolerance. DMAP was found to be crucial for successful transformation, and the reaction likely proceeds via a Ni(0)/Ni(II) catalysis based on mechanistic studies. The method was also successfully extended to aryl bromides and aryl iodides.

Process for preparing nitriles

A heteroaromatic nitrile is prepared in a high selectivity and yield by catalytically reacting an alkyl-substituted heteroaromatic compound with molecular oxygen and ammonia in a molar ratio of oxygen to ammonia of not larger than 1.6:1 in a gaseous phase in the presence of a catalyst comprising a vanadium-phosphorus oxide of the formula: wherein x, y and z represent atomic ratios of phosphorus, antimony and oxygen to vanadium, respectively, and x is from 0.1 to 5, y is 0 to 8 and z is defined from the valencies of other elements.