119507-34-5Relevant academic research and scientific papers
UNSATURATED CARBOXYLIC ACID POLYENOLATES. LITHIUM TRIENOLATE OF SORBIC ACID AS d6 SYNTHON: ADDITION TO KETONES AND UNSATURATED KETONES
Ballester, Pablo,Costa, Antonio,Garcia-Raso, Angel,Mestres, Ramon
, p. 2797 - 2804 (2007/10/02)
Deprotonation of sorbic acid by two equivalents of lithium diethylamide, and aldol-type reaction of the resulting trienolate dianion (2) with carbonylic compounds affords the pentadienyl hydroxy acids (6) or 7-hydroxyhexa-2,4-dienoic acids (7) according to the duration of the reaction.The reaction of the dianion (2) with α,β-unsaturated ketones gives 1,4-ε-adducts for di- or tri-substituted enones, but either 1,4-γ- or 1,4-α-adducts for monosubstituted enones.
