1195070-44-0

Basic information

• Product Name: propane-1-sulfonic acid {2-fluoro-3-[hydroxy-(7H-pyrrolo[2,3-d]pyrimidin-5-yl)-methyl]-phenyl}-amide
• Synonyms: propane-1-sulfonic acid {2-fluoro-3-[hydroxy-(7H-pyrrolo[2,3-d]pyrimidin-5-yl)-methyl]-phenyl}-amide
• CAS NO: 1195070-44-0
• Molecular Weight: 364.4
• Mol File: 1195070-44-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: propane-1-sulfonic acid {2-fluoro-3-[hydroxy-(7H-pyrrolo[2,3-d]pyrimidin-5-yl)-methyl]-phenyl}-amide(CAS DataBase Reference)
• NIST Chemistry Reference: propane-1-sulfonic acid {2-fluoro-3-[hydroxy-(7H-pyrrolo[2,3-d]pyrimidin-5-yl)-methyl]-phenyl}-amide(1195070-44-0)
• EPA Substance Registry System: propane-1-sulfonic acid {2-fluoro-3-[hydroxy-(7H-pyrrolo[2,3-d]pyrimidin-5-yl)-methyl]-phenyl}-amide(1195070-44-0)

Safety Data

• Hazardous Substances Data: 1195070-44-0(Hazardous Substances Data)

Upstream product

• 918523-78-1 propane-1-sulfonic acid (2-fluoro-3-formyl-phenyl)-amide 
• 271-70-5 7H-pyrrolo[2,3-d]pyrimidine 

Downstream Products

• 1195070-46-2 propane-1-sulfonic acid [2-fluoro-3-(7H-pyrrolo[2,3-d]pyrimidine-5-carbonyl)-phenyl]-amide 

Relevant articles and documents

COMPOUNDS AND METHODS FOR KINASE MODULATION, AND INDICATIONS THEREFOR

Compounds and salts thereof, formulations thereof, conjugates thereof, derivatives thereof, forms thereof and uses thereof are described. In certain aspects and embodiments, the described compounds or salts thereof, formulations thereof, conjugates thereof derivatives thereof, forms thereof are active on at least one Raf protein kinase. Also described are methods of use thereof to treat diseases and conditions, including diseases and conditions associated with activity of Raf protein kinases, including melanoma, colorectal cancer, thyroid cancer, ovarian cancer, cholangiocarcinoma, pain or polycystic kidney disease.