119577-28-5 Usage
General Description
7-Ethyl-10-hydroxycamptothecin, also known as SN-38, is a potent derivative of camptothecin, a quinoline alkaloid native to the tree Camptotheca acuminata. 7-ETHYL-10-HYDROXYCAMPTOTHECIN,98% possesses a 98% purity level. It is primarily known for its use as an antitumor agent in the field of chemotherapy. SN-38 acts by inhibiting the DNA enzyme Topoisomerase I, thus preventing cancer cell replication and promoting programmed cell death (apoptosis). Notably, it is the active metabolite of the prodrug Irinotecan, a commonly used chemotherapeutic medication. Its biologically active form makes it a highly effective cytotoxic agent against a range of cancer types.
Check Digit Verification of cas no
The CAS Registry Mumber 119577-28-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,1,9,5,7 and 7 respectively; the second part has 2 digits, 2 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 119577-28:
(8*1)+(7*1)+(6*9)+(5*5)+(4*7)+(3*7)+(2*2)+(1*8)=155
155 % 10 = 5
So 119577-28-5 is a valid CAS Registry Number.
InChI:InChI=1/C20H16N2O5/c1-2-20(26)13-7-15-17-10(6-11-14(21-17)4-3-5-16(11)23)8-22(15)18(24)12(13)9-27-19(20)25/h3-7,23,26H,2,8-9H2,1H3/t20-/m0/s1
