119595-00-5

Basic information

• Product Name: (+/-)-(trans-cyclohex-4-ene-1,2-diyl)-di-acetonitrile
• Synonyms: (+/-)-(trans-cyclohex-4-ene-1,2-diyl)-di-acetonitrile
• CAS NO: 119595-00-5
• Molecular Weight: 160.219
• Mol File: 119595-00-5.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (+/-)-(trans-cyclohex-4-ene-1,2-diyl)-di-acetonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: (+/-)-(trans-cyclohex-4-ene-1,2-diyl)-di-acetonitrile(119595-00-5)
• EPA Substance Registry System: (+/-)-(trans-cyclohex-4-ene-1,2-diyl)-di-acetonitrile(119595-00-5)

Safety Data

• Hazardous Substances Data: 119595-00-5(Hazardous Substances Data)

Upstream product

• 7500-58-5 trans-4,5-bis(hydroxymethyl)cyclohexene bis(toluene-p-sulfonate) 
• 143-33-9 sodium cyanide 
• 20246-03-1 (1R,2R)-bis<(p-toluenesulfonyloxy)methyl>-4-cyclohexene 

Downstream Products

• 3716-38-9 (+/-)-trans-bicyclo<4.3.0>nonan-3β-ol 
• 41065-46-7 (+/-)-2-Amino-3-cyan-3ar,4,7,7at-tetrahydro-1H-inden 
• 119595-01-6 trans-4,5-bis(carboxymethyl)cyclohexene 

Relevant articles and documents

[6+5] FUSED BICYCLES AS A THROMBIN ANTAGONIST, PROCESS FOR PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE BICYCLES

The present invention relates to the new [6+5] fused bicycle derivatives, pharmaceutically acceptable salts or isomers thereof, processes for preparing the same, and pharmaceutical compositions comprising the same. The [6+5] fused bicycle derivatives can antagonize the thrombin receptor and thus may be effectively used for the treatment and prevention of thrombus, platelet aggregation, atherosclerosis, restenosis, blood coagulation, hypertension, arrhythmia, angina pectoris, heart failure, inflammation and cancer when used alone or with other cardiovascular agents.