1195960-50-9Relevant academic research and scientific papers
Cycloisomerization of aromatic homo and bis-homopropargylic alcohols via catalytic ru vinylidenes: Formation of benzofurans and isochromenes
Varela-Fernandez, Alejandro,Gonzalez-Rodriguez, Carlos,Varela, Jesus A.,Castedo, Luis,Saa, Carlos
supporting information; experimental part, p. 5350 - 5353 (2009/12/30)
Ru-catalyzed cycloisomerizations of aromatic homo- and bis-homopropargylic alcohols effectively afford benzofurans and isochromenes. These processes proved to be chemo- and regioselective (5-, and 6-endo cyclizations) derived from key Ru vinylidene intermediates. The presence of an amine/ammonium base-acid pair is crucial for the catalytic cycle.
