1195989-74-2Relevant academic research and scientific papers
Synthesis of substituted imidazo[1,5-a]pyrazines via Mono-, Di-, and directed remote metalation strategies
Board, Johnathan,Wang, Jian-Xin,Crew, Andrew P.,Jin, Meizhong,Foreman, Kenneth,Mulvihill, Mark J.,Snieckus, Victor
, p. 5118 - 5121 (2009)
Imidazo[1,5-a]pyrazines 1 undergo regioselective C3-metalation and C5/C3-dimetalation to afford a range of functionalized derivatives 2a-2g (Table 1), and 4a-4d (Table 2). Under similar conditions, the C3-methyl derivatives 2a and 5 undergo surprising reg
