119604-68-1

Upstream product

• 119580-47-1 2,2'-(((benzylazanediyl)bis(ethane-2,1-diyl))bis(oxy))diethanol 
• 37002-45-2 (4S,5S)-2,2-dimethyl-4,5-bis(p-toluenesulfonyloxymethyl)-1,3-dioxolan 

Relevant academic research and scientific papers

Macroheterocycles. 34. Synthesis and Enantiomeric Selectivity of Chiral Azacrown

Chiral azacrown ethers were obtained by the condensation of (4S,5S)-4,5-ditosyloxymethyl-2,2-dimethyl-1,3-dioxolane with 6-benzyl-3,9-dioxa-6-azaundecane-1,11-diol.Their debenzylation and deacetalization were realized.The enantiomeric selectivity in the complex formation between the obtained crown ethers and the hydrochlorides of L- and D-valine methyl esters was determined by a potentiometric method.The chiral azacrown ethers exhibit higher enantioselectivity than their oxygen analogs.