119604-69-2Relevant academic research and scientific papers
Macroheterocycles. 34. Synthesis and Enantiomeric Selectivity of Chiral Azacrown
Luk'yanenko, N. G.,Lobach, A. V.,Nazarova, N. Yu.,Karpenko, L. P.,Lyamtseva, L. N.
, p. 562 - 566 (2007/10/02)
Chiral azacrown ethers were obtained by the condensation of (4S,5S)-4,5-ditosyloxymethyl-2,2-dimethyl-1,3-dioxolane with 6-benzyl-3,9-dioxa-6-azaundecane-1,11-diol.Their debenzylation and deacetalization were realized.The enantiomeric selectivity in the complex formation between the obtained crown ethers and the hydrochlorides of L- and D-valine methyl esters was determined by a potentiometric method.The chiral azacrown ethers exhibit higher enantioselectivity than their oxygen analogs.
