1196053-11-8

Basic information

• Product Name: BenzaMide, N-[(1S)-3-[4-(2-aMinocyclopropyl)phenoxy]-1-[[(phenylMethyl)aMino]carbonyl]propyl]-, hydrochloride (1:1)
• Synonyms: BenzaMide, N-[(1S)-3-[4-(2-aMinocyclopropyl)phenoxy]-1-[[(phenylMethyl)aMino]carbonyl]propyl]-, hydrochloride (1:1);N-[(2S)-4-[4-(2-aminocyclopropyl)phenoxy]-1-(benzylamino)-1-oxobutan-2-yl]benzamide:hydrochloride
• CAS NO: 1196053-11-8
• Molecular Formula: C₂₇H₂₉N₃O₃*ClH
• Molecular Weight: 480.01
• Mol File: 1196053-11-8.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: BenzaMide, N-[(1S)-3-[4-(2-aMinocyclopropyl)phenoxy]-1-[[(phenylMethyl)aMino]carbonyl]propyl]-, hydrochloride (1:1)(CAS DataBase Reference)
• NIST Chemistry Reference: BenzaMide, N-[(1S)-3-[4-(2-aMinocyclopropyl)phenoxy]-1-[[(phenylMethyl)aMino]carbonyl]propyl]-, hydrochloride (1:1)(1196053-11-8)
• EPA Substance Registry System: BenzaMide, N-[(1S)-3-[4-(2-aMinocyclopropyl)phenoxy]-1-[[(phenylMethyl)aMino]carbonyl]propyl]-, hydrochloride (1:1)(1196053-11-8)

Safety Data

• Hazardous Substances Data: 1196053-11-8(Hazardous Substances Data)

Upstream product

• 1196053-09-4 (S)-trans-{2-[4-(3-benzoylamino-3-benzylcarbamoylpropoxy)phenyl]}cyclopropyl tert-butyl carbamate 

Relevant articles and documents

Identification of cell-active lysine specific demethylase 1-selective inhibitors

(Chemical Equation Presented) Lysine specific demethylase 1 (LSD1) plays a key role in the regulation of gene expression by removing the methyl groups from methylated Lys4 of histone H3 (H3K4). Here we report the identification of the first small-molecule LSD1-selective inhibitors. These inhibitors show in vivo H3K4-methylating activity and antiproliferative activity and should be useful as lead structures for anticancer drugs and as tools for studying the biological roles of LSD1.