1196133-39-7 Usage
Uses
LGD-3303 is used in methods reducing mammographic breast density and/or breast cancer risk comprising the administration of an effective administration of an androgenic agent and an effective amt. of an aromatase inhibitor. LGD-3303 is also used in combination with anti-TWEAK antibodies for treating muscle atrophy.
Biotechnological Applications
LGD-3303 is a selective agonist for the androgen receptor, producing functional selectivity with effective dissociation of anabolic and androgenic effects, acting as a partial agonist for androgenic effects, but a full agonist for anabolic effects.It has been investigated as a possible treatment for osteoporosis, and was shown in animal studies to enhance the effectiveness of a bisphosphonate drug.
Check Digit Verification of cas no
The CAS Registry Mumber 1196133-39-7 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,1,9,6,1,3 and 3 respectively; the second part has 2 digits, 3 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 1196133-39:
(9*1)+(8*1)+(7*9)+(6*6)+(5*1)+(4*3)+(3*3)+(2*3)+(1*9)=157
157 % 10 = 7
So 1196133-39-7 is a valid CAS Registry Number.
1196133-39-7Relevant articles and documents
Androgen Receptor Modulator Compounds and Methods
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Page/Page column 52, (2009/02/11)
Provided herein are compounds that bind to androgen receptors and/or modulate activity of androgen receptors, and to methods for making and using such compounds. Also provided are compositions including such compounds and methods for making and using such compositions.