119618-22-3

Basic information

• Product Name: (S)-Oxybutynin
• Synonyms: (S)-OXYBUTYNIN CHLORIDE;(S)-OXYBUTYNIN HCL;(S)-OXYBUTYNIN HYDROCHLORIDE;(S)-A-PHENYLCYCLOHEXANEGLYCOLIC ACID 4-(DIETHYLAMINO)-2-BUTYNYL ESTER, HYDROCHLORIDE;(S)-CYCLOHEXYL-HYDROXY-PHENYL-ACETIC ACID 4-DIETHYLAMINO-BUT-2-YNYL ESTER;(S)-Oxybutynin;Benzeneacetic acid, a-cyclohexyl-a-hydroxy-, 4-(diethylamino)-2-butynyl ester, (aS)- (9CI);Benzeneacetic acid, a-cyclohexyl-a-hydroxy-, 4-(diethylamino)-2-butynyl ester, (S)-
• CAS NO: 119618-22-3
• Molecular Formula: C₂₂H₃₁NO₃
• Molecular Weight: 357.49
• Product Categories: Chiral Reagents;Inhibitors;Intermediates & Fine Chemicals;Pharmaceuticals
• Mol File: 119618-22-3.mol
• Article Data: 5

Chemical Properties

• Melting Point: 52-54°C
• Boiling Point: 494.383 °C at 760 mmHg
• Flash Point: 252.794 °C
• Appearance: Off-white solid
• Density: 1.097
• Vapor Pressure: 1.37E-10mmHg at 25°C
• Refractive Index: 1.546
• Storage Temp.: Refrigerator, Under Inert Atmosphere
• Solubility: Chloroform (Slightly), Ethanol (Slightly)
• PKA: 11.95±0.29(Predicted)
• CAS DataBase Reference: (S)-Oxybutynin(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-Oxybutynin(119618-22-3)
• EPA Substance Registry System: (S)-Oxybutynin(119618-22-3)

Safety Data

• Hazardous Substances Data: 119618-22-3(Hazardous Substances Data)

Usage

Chemical Properties

Off-White Solid

InChI:InChI=1/C22H31NO3/c1-3-23(4-2)17-11-12-18-26-21(24)22(25,19-13-7-5-8-14-19)20-15-9-6-10-16-20/h5,7-8,13-14,20,25H,3-4,6,9-10,15-18H2,1-2H3/t22-/m0/s1

Upstream product

• 1508-65-2 Oxybutynin chloride 
• 22396-77-6 acetic acid-(4-diethylamino-but-2-ynyl ester) 
• 10399-13-0 methyl 2-cyclohexyl-2-hydroxy-2-phenylacetate 
• 10575-25-4 4-diethylamino-2-butyn-1-ol 
• 4335-77-7 cyclohexylmandelic acid 

Downstream Products

• 1508-65-2 Oxybutynin chloride 
• 80976-67-6 4-(ethylamino)-2-butynyl α-cyclohexyl-α-hydroxybenzeneacetate 
• 688364-67-2 4-(diethylmethylaminium)-2-butynyl alpha phenyl cyclohexane glycolate iodide 
• 10575-25-4 4-diethylamino-2-butyn-1-ol 
• 4335-77-7 cyclohexylmandelic acid 

Relevant articles and documents

POLYMORPHIC FORMS OF (R)-OXYBUTYNIN HYDROCHLORIDE

Polymorphic forms of (R)-oxybutynin HC1, including three crystalline forms, are prepared and characterized. Uses of the various polymorphic forms of (R)-oxybutynin HC1 for Obstructive Sleep Apnea (OS A) treatment are also disclosed.

CRYSTALLINE OXYBUTYNIN AND PROCESS FOR PREPARING THE SAME

The present invention relates to a crystalline oxybutynin base and process for preparing the same. Further, this invention discloses a process for preparing an acid addition salt of oxybutynin employing the crystalline oxybutynin base.

QUATERNARY AMMONIUM COMPOUNDS

The invention features quaternary ammonium compounds of formula I, described herein, and their use in treating asthma, chronic obstructive pulmonary disorder, allergic rhinitis, and infectious rhinitis.