119643-69-5

Basic information

• Product Name: boc-octreotide
• Synonyms: boc-octreotide
• CAS NO: 119643-69-5
• Molecular Weight: 1119.37
• Mol File: 119643-69-5.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: boc-octreotide(CAS DataBase Reference)
• NIST Chemistry Reference: boc-octreotide(119643-69-5)
• EPA Substance Registry System: boc-octreotide(119643-69-5)

Safety Data

• Hazardous Substances Data: 119643-69-5(Hazardous Substances Data)

Upstream product

• 13139-12-3 tert-butyl 2,5-dioxopyrrolidin-1-yl carbonate 
• 79517-01-4 octreotide acetate 
• 24424-99-5 di-tert-butyl dicarbonate 
• 83150-76-9 octreotide 

Relevant articles and documents

IMPROVED CONJUGATION LINKERS

Provided are β-eliminative linkers suitable for the conjugation of small molecule, peptide, and protein and compounds comprising the linkers.

A method for preparing covalent lipid-spacer-peptide conjugates

The present invention discloses a method for preparing lipid-spacer-reactive functional group-peptide, wherein the peptide consists of 3 to 16 amino acid residues in which at least one amino acid residue is lysine (Lys), the reactive functional group is a formula of -X-CO-Y-CO-, wherein X represents an oxygen atom or a nitrogen atom, and Y represents C1-6 alkylene which may be interrupted by one or two oxygen or nitrogen atom(s), the spacer is a hydrophilic polymer, and the lipid is phosphatidylethanoaminecarbonyl represented by the formula (I): R1 and R2 are the same or different and individually represent linear or branch C7-30 alkyl or linear or branch C7-30 alkenyl; which is characterized in that the reaction is carried out in a liquid phase and comprises the following steps of (a) firstly protecting Lys amino acid residue in the peptide through a protection group; (b) subsequently reacting the peptide with the lipid-spacer-reactive functional group; and (c) finally removing the protection group from Lys amino acid residue in the peptide.