1196466-62-2Relevant academic research and scientific papers
Synthesis and cytotoxicity studies of new cryptophycin analogues
Wen, Lu Liu,Jian, Cun Zhang,Fa, Qin Jiang,Fu, Lei
experimental part, p. 577 - 583 (2009/12/24)
Two analogues of cryptophycin were synthesized and biologically evaluated for their in-vitro cytotoxicities against several solid tumors and leukemia cell lines. The results revealed that both analogues exhibited a broad range of cytotoxic activity with observed IC50 values in the μM-range, and compound 4 was more effective than compound 3 in most assays studied.
