1196516-91-2Relevant academic research and scientific papers
High-throughput discovery of mycobacterium tuberculosis protein tyrosine phosphatase B (MptpB) inhibitors using click chemistry
Tan, Lay Pheng,Wu, Hao,Yang, Peng-Yu,Kalesh, Karunakaran A.,Zhang, Xiaohua,Hu, Mingyu,Srinivasan, Rajavel,Yao, Shao Q.
supporting information; experimental part, p. 5102 - 5105 (2010/03/24)
A ～500-member library of bidentate inhibitors against protein tyrosine phosphatases (PTPs) was rapidly assembled using click chemistry. Subsequent high-throughput screening had led to the discovery of highly potent (K i as low as 150 nM) and se
