1196530-96-7Relevant academic research and scientific papers
Asymmetrie Conjugate reductions of coumarins. A new route to tolterodine and related coumarin derivatives
Gallagher, Brian D.,Taft, Benjamin R.,Lipshutz, Bruce H.
supporting information; experimental part, p. 5374 - 5377 (2010/02/28)
"Chemical Equation Presented" The combination of catalytic amounts of [(R)-DTBM-SEGPHOS]CUH In the presence of stoichiometric DEMS (dlethoxymethylsllane) In toluene at room temperature leads to asymmetric reductions of 4-substituted coumarins. Several targets or their known precursors can be prepared In high yields and ee's, Including the muscarine receptor antagonist (R)-tolterodine.
