1196712-27-2Relevant academic research and scientific papers
Hypervalent Iodine/HF Reagents for the Synthesis of 3-Fluoropyrrolidines
Kitamura, Tsugio,Miyake, Azusa,Muta, Kensuke,Oyamada, And Juzo
, p. 11721 - 11726 (2017)
The intramolecular aminofluorination of homoallylamine derivatives using a reagent system of PhI(OAc)2 and Py·HF in CH2Cl2 at room temperature for 5 h gave N-tosyl-3-fluoropyrrolidines in good to high yields. Furthermore, the catalytic aminofluorination was furnished by the reaction using p-iodotoluene as a catalyst in the presence of Py·HF as a fluorine source and mCPBA as a terminal oxidant.
Transition-metal-free visible-light photoredox catalysis at room-temperature for decarboxylative fluorination of aliphatic carboxylic acids by organic dyes
Wu, Xinxin,Meng, Chunna,Yuan, Xiaoqian,Jia, Xiaotong,Qian, Xuhong,Ye, Jinxing
supporting information, p. 11864 - 11867 (2015/07/20)
We report herein an efficient, general and green method for decarboxylative fluorination of aliphatic carboxylic acids. By using a transition-metal-free, organocatalytic photoredox system, the reaction of various aliphatic carboxylic acids with the Select
Regioselective (Diacetoxyiodo)benzene-promoted halocyclization of unfunctionalized olefins
Liu, Gong-Qing,Li, Yue-Ming
, p. 10094 - 10109 (2015/02/19)
A metal-free method for intramolecular halocyclization of unfunctionalized olefins was detailed. (Diacetoxyiodo)benzene (PIDA) was very effective for haloamidation, haloetherification, and halolactonization of unfunctionalized olefins. In the presence of
Regio- and enantioselective aminofluorination of alkenes
Kong, Wangqing,Feige, Pascal,De Haro, Teresa,Nevado, Cristina
supporting information, p. 2469 - 2473 (2013/03/29)
Enantio- and regioselective: The intramolecular enantioselective aminofluorination of unactivated olefins was achieved by using a chiral iodo(III) difluoride salt. A highly regioselective aminofluorination of styrenes to access 2-fluoro-2-phenylethanamines was also developed. Copyright
Metal-free intramolecular aminofluorination of alkenes mediated by PhI(OPiv)2/hydrogen fluoride-pyridine system
Wang, Qing,Zhong, Wenhe,Wei, Xiong,Ning, Maoheng,Meng, Xiangbao,Li, Zhongjun
supporting information, p. 8566 - 8569 (2013/01/15)
A convenient, metal-free intramolecular aminofluorination of alkenes has been developed. Employing readily available PhI(OPiv)2 and hydrogen fluoride-pyridine in the presence of BF3·OEt2, tosyl-protected pent-4-en-1-amines were converted to 3-F-piperidines in one step in good yields as well as high stereoselectivity.
Palladium-catalyzed intramolecular aminofluorination of unactivated alkenes
Wu, Tao,Yin, Guoyin,Liu, Guosheng
supporting information; experimental part, p. 16354 - 16355 (2010/01/30)
(Chemical Equation Presented) A novel palladium-catalyzed intramolecular oxidative aminofluorination of unactivated alkenes has been developed, in which AgF was used as a key fluorinating reagent and PhI(OPiv)2 as oxidant. The reaction afforded
