1196791-31-7Relevant academic research and scientific papers
Studies of the asymmetric total synthesis of clavilactone D by the 'lariat' cyclization strategy
Yoshimitsu, Takehiko,Nojima, Shoji,Hashimoto, Masashi,Tsukamoto, Koji,Tanaka, Tetsuaki
, p. 2963 - 2969 (2009)
A route to the core structure of clavilactone D, a new member of the tyrosine kinase inhibitors, is reported. The route employs sequential cyclization initiated by iodo etherification followed by Friedel-Crafts cyclization to furnish a polycyclic lactone
