119680-01-2Relevant academic research and scientific papers
Conjugate Addition of Grignard Reagents to Enones and Dienones
Modi, Sandeep P.,Gardner, John O.,Milowsky, Arnold,Wierzba, Mark,Forgione, Lisa,et al.
, p. 2317 - 2321 (2007/10/02)
Grignard reaction with 16-dehydropregnenolone acetate, 1, results in 1,4-addition to the enone system.Introduction of even trace amounts of oxygen before the reaction has been fully quenched results in formation of 17α-hydroperoxides as well as the expect
