119680-05-6

Upstream product

• 6553-96-4 2,4,6-triisopropylphenylsulfonyl chloride 
• 6979-97-1 3',5'-diacetylthymidine 

Downstream Products

• 848641-23-6 Acetic acid (2R,3S,5R)-2-acetoxymethyl-5-{5-methyl-4-[2-(2-nitro-phenyl)-ethoxy]-2-oxo-2H-pyrimidin-1-yl}-tetrahydro-furan-3-yl ester 
• 110085-56-8 Acetic acid (2R,3S,5R)-2-acetoxymethyl-5-(4-benzyloxy-5-methyl-2-oxo-2H-pyrimidin-1-yl)-tetrahydro-furan-3-yl ester 
• 119680-16-9 5-O-(Dimethoxytrityl)-2-deoxy-1-β-<4-methyl-1-oxo-2-(2H)-naphth<2',3':4,5>imidazo<1,2-f>pyrimidinyl>-3-O-ribofuranosylphosphonate triethylammonium salt 
• 119680-18-1 5-O-(Dimethoxytrityl)-2-deoxy-1-β-<5-methyl-2-oxo-(3H)pyrimido<1,6-a>perimidin-3-yl>-3-O-ribofuranosylphosphonate triethylammonium salt 
• 119680-14-7 5-Methyl-3-<5-O-(dimethoxytrityl)-2-deoxy-1-β-D-ribofuranosyl>pyrimido<1,6-a>perimidin-2(3H)-one 
• 119693-96-8 4-Methyl-2-<5-O-(dimethoxytrityl)-2-deoxy-1-β-D-ribofuranosyl>-naphth<2',3':4,5>imidazo<1,2-f>pyrimidin-1(2H)-one 
• 169213-21-2 4-Benzyloxy-1-{(2R,4S,5R)-5-[bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-4-hydroxy-tetrahydro-furan-2-yl}-5-methyl-1H-pyrimidin-2-one 
• 848641-32-7 1-((2R,4S,5R)-4-Hydroxy-5-hydroxymethyl-tetrahydro-furan-2-yl)-5-methyl-4-[2-(2-nitro-phenyl)-propoxy]-1H-pyrimidin-2-one 
• 848641-31-6 1-((2R,4S,5R)-4-Hydroxy-5-hydroxymethyl-tetrahydro-furan-2-yl)-5-methyl-4-[2-(2-nitro-phenyl)-ethoxy]-1H-pyrimidin-2-one 
• 848641-29-2 1-((2R,4S,5R)-4-Hydroxy-5-hydroxymethyl-tetrahydro-furan-2-yl)-5-methyl-4-(2-nitro-benzyloxy)-1H-pyrimidin-2-one 
• 848641-30-5 1-((2R,4S,5R)-4-Hydroxy-5-hydroxymethyl-tetrahydro-furan-2-yl)-5-methyl-4-[1-(2-nitro-phenyl)-ethoxy]-1H-pyrimidin-2-one 

Relevant academic research and scientific papers

Bioreductive deprotection of 4-nitrobenzyl group on thymine base in oligonucleotides for the activation of duplex formation

Oligonucleotides containing 4-O-(4-NO2-benzyl)thymine residues were synthesized to assess potential prodrug-type action against hypoxic cells. These modified oligonucleotides were incapable of stable duplex formation under non-hypoxic condition

Photoinduced transcription by using temporarily mismatched caged oligonucleotides

Spatial and temporal control of the function of DNA with light: In oligonucleotides, protected ("caged") thymidine can act as a temporary mismatch in base pairing and, for example, prevent transcription. The photolabile caging group can be removed by ligh