1196887-34-9

Upstream product

• 1196887-30-5 ethyl 4-((1R,4R)-4-(tert-butyldimethylsilyloxy)cyclohexylcarbamoyl)-1H-imidazole-2-carboxylate 
• 1196887-15-6 2-(ethoxycarbonyl)-1H-imidazole-5-carboxylic acid 

Downstream Products

• 1196887-32-7 N-((1S,4S)-4-(tert-butyldimethylsilyloxy)cyclohexyl)-2-formyl-1H-imidazole-4-carboxamide 
• 1196991-13-5 (Z)-2-((2-amino-4-chloro-7-((4-methoxy-3,5-dimethylpyridin-2-yl)methyl)-6-oxo-6,7-dihydro-5H-pyrrolo[2,3-d]pyrimidin-5-ylidene)methyl)-N-(4-hydroxycyclohexyl)-1H-imidazole-4-carboxamide 

Relevant academic research and scientific papers

BIOACTIVE COMPOUNDS FOR TREATMENT OF CANCER AND NEURODEGENERATIVE DISEASES

The invention provides bioactive compounds for the treatment of various malconditions such as cancer and neurodegenerative diseases including Alzheimer's disease. The chemical compounds as disclosed herein are found to show bioactivity in bioassays related to these conditions. Pharmaceutical compositions, combinations and methods of synthesis are provided, as are methods of using the compound, compositions and combinations in the treatment of the diseases.