1197-57-5

Upstream product

• 873-76-7 para-Chlorobenzyl alcohol 
• 88023-84-1 (4-chlorobenzyl)methyl thiomethyl ether 

Downstream Products

• 115171-54-5 5-chloro-2-(4-chlorobenzyloxy)methoxypyrimidine 
• 88045-78-7 5-chloro-1-(4-chlorobenzyloxy)methyl-2(1H)-pyrimidinone 
• 88045-91-4 1-(4-Chlorobenzyloxy)methyl-5-fluoropyrimidin-2-one 
• 136160-43-5 1-(4-Chloro-benzyloxymethyl)-5-ethyl-6-phenylsulfanyl-2-thioxo-2,3-dihydro-1H-pyrimidin-4-one 
• 115171-60-3 bis(trimethylsilyl) 5-chloro-1-(4-chlorobenzyloxy)methyl-2-oxo-3-trimethylsilyl-3,4-dihydropyrimidine-4-phosphonate 
• 115171-62-5 5-chloro-1-(4-chlorobenzyloxy)methyl-2-oxo-3,4-dihydropyrimidine-4-phosphonic acide 
• 14289-63-5 1-chloro-4-(2-propenyloxymethyl)benzene 

Relevant academic research and scientific papers

NOVEL PYRIMIDINE NUCLEOSIDE COMPOUNDS OR SALTS THEREOF

PROBLEM TO BE SOLVED: To provide novel pyrimidine nucleoside compounds that exhibit an excellent balance between antitumor effect and toxicity compared to existing pyrimidine nucleoside compounds. SOLUTION: The present invention provides pyrimidine nucleoside compounds represented by the general formula (1) in the figure or salts thereof. COPYRIGHT: (C)2015,JPOandINPIT

Synthesis and nucleophilic substitution reactions of mono α-fluoro ethers

Mono α-fluoro ethers have been prepared by cleavage of α-alkoxy sulfoxides with diethylaminosulfur trifluoride (DAST) and by an exchange reaction of the corresponding α-chloro ether with tetrabutylammonium fluoride (TBAF). The reactivity of different α-fluoro ethers in some nucleophilic substitution reactions has been investigated. Copyright Acta Chemica Scandinavica 1999.