1197006-53-3Relevant academic research and scientific papers
Nitrile Ylides: Diastereoselective cycloadditions using chiral oxzolidinones without Lewis acid
Mukund P, Sibi,Soeta, Takahlro,Jasperse, Craig P.
, p. 5366 - 5369 (2009)
"Chemical Equation Presented" Lewis acid complexation Is generally required for chiral-auxiliary-controlled stereoselectivity, and chiral Lewis acid catalysis Is frequently optimal for Introducing asymmetry. In this work, we show that nitrlle ylide cycloadditions to electron-poor acceptors attached to chiral auxiliaries proceed In high yield and stereoselectivity in the absence of Lewis acids. In contrast, chiral Lewis acids are Inferior In these cycloadditions.
